Senior Backend Engineer

August 26, 2025

Closed

Location

Anywhere

Occupation

Full-time

Experience level

Senior

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AI Summary

Plexis.ai, a Techstars '25 company focused on transforming healthcare through advanced AI solutions, is hiring a Senior Backend Engineer for a full-time, fully remote role based out of Hanoi, Vietnam. In this position, you'll lead backend development for systems that integrate AI models to streamline administrative healthcare tasks, significantly cutting operational costs. Responsibilities include designing scalable systems using Python and FastAPI, integrating large language models (LLMs) such as GPT or Claude via APIs, maintaining secure data infrastructure with PostgreSQL, and collaborating with the wider engineering and product teams. The role offers a unique opportunity to work at the intersection of AI and healthcare, with perks like employee stock options based on performance, fast-paced learning in deep-tech, and early-stage startup experience.

The ideal candidate brings at least 5+ years of backend development experience, particularly with Python and FastAPI. A strong background in AI/ML model integration—such as using OpenAI or Hugging Face APIs—is crucial. You should have database management experience (PostgreSQL or MongoDB), knowledge of RESTful API design and microservices architecture, and familiarity with deploying machine learning models in production. Bonus points if you're experienced with orchestration tools like Celery or Prefect. Strong problem-solving abilities and a meticulous attention to detail are essential.

Plexis.ai offers an exciting chance to help build the backbone of AI use in healthcare, with access to cutting-edge technologies and a mission-driven team. As part of a Techstars-backed startup, you'll have the opportunity to shape impactful solutions in a critical industry while advancing your tech career in a deep-tech environment.

Company Description

Plexis.ai, a Techstars '25 company, is pioneering the development of AI clinical infrastructure in healthcare. Our adaptive AI agents handle administrative tasks within existing systems, offering an average of 40% cost savings. As a trusted partner, Plexis.ai ensures the safe deployment of AI with guardrails for governance, healthcare-specific agent creation, and continuous performance monitoring.

Role Description

This is a full-time remote role for a Senior Backend Engineer specializing in Python, FastAPI, and AI Integration. The Senior Backend Engineer will be responsible for designing, developing, and implementing backend services. This role involves writing clean, scalable code, integrating AI models, optimizing performance, and ensuring application security. Additionally, the engineer will collaborate with cross-functional teams to define and develop new features.

You will be responsible for building the backend infrastructure, integrating AI models, and ensuring the backend can handle scalability and security.

Responsibilities

Design and implement backend systems using Python (FastAPI) framework to build an orchestration engine. Integrate large language models (LLMs) such as GPT, LLaMA, or Claude through APIs. Build APIs to enable frontend interaction with backend systems (agent creation, workflow automation). Develop and manage data storage solutions (PostgreSQL). Manage fine-tuning workflows for LLMs to meet customer-specific requirements. Ensure data security and compliance with enterprise standards. Optimize system performance and scalability for high usage.